efforts, it’s a signal worth discussing with your doctor.
Trouble Sleeping Beyond nocturia, toxin buildup can make it harder to fall or stay asleep. Many people report restless nights that compound daytime fatigue.10–17. Additional Visible and Noticeable Signs on the Body Continuing the list of signs you might observe: 10. Puffy eyes or facial swelling in the morning. 11. Changes in skin texture, such as roughness or flakiness. 12. Muscle twitches or spasms. 13. Easy bruising or pale skin related to anemia. 14. Headaches or difficulty focusing. 15.