| Reduce secretions including saliva | ||
| Antidepressants (TCAs, SSRIs) | Amitriptyline, Fluoxetine, Sertraline | Anticholinergic effects suppress salivary glands |
| Antipsychotics | Olanzapine, Clozapine, Haloperidol | Strong anticholinergic activity |
| Blood Pressure Medications | Amlodipine, Atenolol, Hydrochlorothiazide | Diuretic effect leads to dehydration |
| Diuretics | Furosemide, Spironolactone | Increase fluid loss, reducing saliva |
| Muscle Relaxants | Cyclobenzaprine, Baclofen | Anticholinergic side effects |
| Bladder Medications | Oxybutynin, Solifenacin | Specifically designed to reduce secretions |
| Parkinson’s Medications | Trihexyphenidyl, Benztropine | High anticholinergic activity |
Important: If you take any of these medications and experience dry mouth, do not stop your medication without medical advice. Speak to your prescribing doctor about