These 10 Common Medications Could Quietly Harm Your Kidneys and Increase Protein in Your Urine

formulations or circumstances involving tenofovir, acyclovir, foscarnet, indinavir and atazanavir.

The mechanism varies.

Some can injure kidney tubules, while others can form crystals or otherwise interfere with normal kidney function.

The actual risk depends on the specific medication, dose, formulation, kidney function, hydration status and other medications being taken.

  1. Certain Cancer and Immunotherapy Drugs

Modern cancer treatments have dramatically improved outcomes for many patients, but some can affect the kidneys.

Examples include certain chemotherapy drugs, targeted therapies and immune checkpoint inhibitors.

The mechanisms vary widely—from direct tubular injury to immune-mediated