The main mechanism is often in the stomach and intestines. Magnesium ions can bind to the active ingredients of these drugs, creating compounds that the body cannot easily absorb.
This is why separation by several hours is frequently recommended. Studies and pharmacy guidelines point to taking the medication first, then waiting before the supplement.
For some other medications like certain diuretics or long term acid reducers, the issue can be the reverse. They may lower magnesium levels in the body over time. In those cases, monitoring through blood tests
